Come, Thou Sanctifier, almighty and eternal God, and bless this sacrifice prepared for the glory of Thy holy name.
As soon as the priest has made the short prayer in which we offer ourselves to God, he raises his head. At the same time he raises his hands toward heaven and prays to the Holy Ghost. He asks the Holy Ghost to bless the offering he is going to make to God at the Consecration of the Mass.
Thou Sanctifier is a name for the Holy Ghost. In the Catechism you learned that the Holy Ghost makes our souls holy through the gift of grace. This is another way for saying that the Holy Ghost sanctifies us.
Taken from The Kingdom of God series The Holy Sacrifice of the Mass by Ellamay Horan. I am not the Author merely the distributor. God Bless BJS!!
Confessions and Commentaries of a Catholic 